Isopropyl Cloprostenate
The History
Isopropyl Cloprostenate is a synthetic prostaglandin analog that has gained attention in the beauty and hair care industries for its role in promoting eyelash, eyebrow, and hair growth. Originally developed for use in ophthalmic treatments, prostaglandin analogs like Isopropyl Cloprostenate were found to have an unexpected side effect: stimulating hair growth in treated areas. Its mechanism mimics that of bimatoprost, the active ingredient in Latisse, which is FDA-approved for eyelash growth. Today, Isopropyl Cloprostenate is included in various over-the-counter serums and topical treatments marketed for hair regrowth and thickening.
The Good
Isopropyl Cloprostenate works by prolonging the anagen (growth) phase of the hair cycle, leading to thicker, fuller hair in areas where it is applied. It also increases the density and pigmentation of hair strands, making them appear darker and healthier. Studies suggest that prostaglandin analogs can stimulate dormant hair follicles and promote regrowth in cases of thinning or sparse hair.
This ingredient is widely used in eyelash and eyebrow growth serums, and its inclusion in scalp-focused products has gained traction due to its ability to deliver targeted benefits with minimal systemic absorption. For individuals looking to improve hair thickness in specific areas, Isopropyl Cloprostenate offers a promising, localized treatment option.
The Bad
While effective for some, Isopropyl Cloprostenate may not be suitable for everyone. Potential side effects include skin irritation, redness, or darkening of the skin around the application site. In rare cases, users may experience eye irritation if the product comes into contact with their eyes. Additionally, while it shows promise for localized hair growth, it may not address widespread or systemic hair loss caused by hormonal imbalances or other underlying conditions.
The Ugly
Isopropyl Cloprostenate products are not FDA-approved for hair loss treatment, and the quality and efficacy of over-the-counter formulations can vary widely. Misleading marketing claims can give users false hope about its effectiveness for more advanced or widespread hair loss. Moreover, discontinuing use often results in the gradual loss of any hair regrowth achieved, meaning it requires consistent, long-term use to maintain results.
How to Get It
Isopropyl Cloprostenate is commonly found in eyelash and eyebrow growth serums but is increasingly included in hair care products targeting thinning hair. These products are typically available over the counter but vary significantly in concentration and quality. As with any cosmetic product, it’s essential to choose formulations from reputable brands and to follow the application instructions carefully.
Which Works Better: Isopropyl Cloprostenate vs. Other Treatments?
Isopropyl Cloprostenate is best suited for individuals looking to improve localized hair density and thickness, particularly in areas like the hairline or eyebrows. However, it is not a replacement for proven systemic treatments like minoxidil or DHT blockers, which address the root causes of hair loss. For individuals with significant or widespread hair thinning, combining Isopropyl Cloprostenate with other treatments may yield better results.
